The 5 Most Effective Supplements for Erectile Dysfunction (ED) in 2025
Written by Robert Wallace
Urologist specialized in erectile dysfunction treatments
First and foremost, it’s important to note that our team doesn’t profit from these analyses. We’re simply doing our job and striving to help as many men as possible prevent and treat erectile dysfunction naturally, with supplements that truly deliver on their promises…
Update on
How to Spot a High-Quality ED Supplement That Actually Delivers.
Are you ready to elevate your performance and reach a new level of well-being? Discover the power of natural testosterone boosters, which have been gaining attention for their ability to transform both physical and mental health. From increased strength and energy to improved focus and vitality, these supplements offer a comprehensive solution for those seeking a more active, healthy, and balanced life.
I’m Dr. Robert Wallace, a urologist with over 25 years of experience helping men regain their sexual health and confidence. After years of testing countless therapies, supplements, and treatments, I’ve learned what really works—and what’s just empty promises.
In this guide, I’ll take you through the top 5 ED supplements that men across the U.S. are using in 2025. My recommendations are based on strict criteria: proven, science-backed ingredients, real-world user results, and a clear focus on effectiveness and value.
If you’re tired of wasting your time and money on solutions that don’t deliver, and you’re finally ready to take control of your sexual health, this guide is for you. Keep reading.
How We Evaluated the Products
To create this review, I evaluated each product based on the following key factors:
Active ingredients: I checked if the ingredients are clinically tested and safe.
Effectiveness: I looked at results reported by real users and scientific studies.
Value for money: I compared pricing and the benefits offered by each product.
Guarantees: I reviewed whether the manufacturer offers a money-back guarantee.
- Scientific Updates: I prioritized products that incorporate the latest scientific discoveries in their formulas. Science is constantly evolving, and it’s crucial to choose supplements that are based on up-to-date research.
Warning Signs of Potential Scams
Lack of Clinical Studies
Be wary of companies that cite the clinical efficacy of individual ingredients within a product rather than the effectiveness of the product as a whole. The highest indicator of quality in a supplement is the commission of a placebo-controlled clinical study for safety and effectiveness by an independent third party. This is of particular importance when assessing the claims of a supplement, as participants can be evaluated for quantifiable performance improvements on a standardized cognitive test. You expect the same high standard of research and testing before trusting a medication, so why wouldn’t you do the same before trusting a supplement?
Unproven Ingredients
There are very few natural ingredients for treating erectile dysfunction that are both effective and safe for consumption. Many products on the market include herbs and compounds that claim to boost performance, but often lack clinical evidence to back up their promises. Be cautious of ED supplements that list an extensive array of ingredients just to create the illusion of comprehensive support. More isn’t always better when it comes to your health. Some supplements we reviewed contained over 10 ingredients—but the question is: are they really necessary?
Shall we analyze?
Prolong Power. A buzzworthy name, and that’s why we decided to find out why. But after looking into it, the reasons behind the hype aren’t as impressive as they seem.
Prolong Power. The name alone grabs attention. Prolong. Enhance. Overcome. But when you look beyond the marketing, the reality is different.
Prolong Power is a product that has gained significant attention in the United States in 2025, being widely discussed due to its promises of exceptional results. Given the growing interest surrounding it, we decided to take a closer look. However, upon examining its raw materials — such as maca root, ginseng, and other popular herbs — we found a formula that, while well-known, offers no real innovation. These are common ingredients found in many other supplements, which leads us to question what truly justifies all the hype.
And what really bothers us? There’s no transparency regarding the dosages or the source of the ingredients. What should be a trustworthy product ends up being nothing more than a list of fancy words and empty jargon. But we did our homework. We conducted detailed studies with these raw materials, analyzing their effectiveness in several patients. And the results? They fell short.
In one of our patient studies, the promised improvement from the formula was not observed in most cases. The response was far below expectations:
“The results were almost nonexistent, I didn’t notice any significant difference.”
“We felt a slight change, but nothing that justified the investment.”
Top 5 Testosterone Boosters of 2025
When analyzing the top 5 best-selling supplements in recent months, we were surprised. We found a product that passed all of our tests with flying colors: Nitric Boost. All of the ingredients mentioned were truly present in our analysis. We decided to take the research a step further and test it on some of our patients, and the benefits were clear. Nitric Boost not only proved to be effective in improving circulation and blood flow, but also helped increase energy and endurance, providing superior performance in physical activities. Additionally, many reported faster recovery and less fatigue, which is a big advantage compared to the other products we analyzed.
And the best part? We didn’t hear any reports of increased blood pressure or headaches, which are common side effects in similar supplements.
Below, we’ve broken down our rankings and provided in-depth reviews of the 5 erectile dysfunction products we reviewed, starting with our top pick and why.
#1 Nitric Boost
9.8 / 10
TOTAL RANKING
A+
Overall Grade
Pros
- Contains must-have ingredients to optimize testosterone levels and enhance sexual performance.
- Molecular formula similar to others on the market without the side effects.
- Vegan, non-GMO, and gluten-free
- Made in the USA in an FDA Approved facility.
- After 40 days of daily use, study participants reported surprising results, including increased testosterone levels, size, and performance.
- Laboratory tests reveal 100% pure ingredients with no binders or fillers.
Cons
- Available online in the United States, but not currently sold in retail stores
- Nitric Boost is for adults 18+ only. Not for use by anyone under 18.
The final result
We gave Nitric Boost our #1 rating because it’s the only erectile dysfunction product that meets all of our rigorous criteria, plus delivers real, sustainable results in treating erectile dysfunction at its root cause.
In just 40 days, participants in our study reported impressive results. Nitric Boost has rapidly earned top ratings from users for boosting energy and enhancing sexual performance, securing its place as one of the leading solutions for erectile dysfunction (ED).
So, what makes Nitric Boost different? It targets the root cause of ED: the buildup of toxins in the interstitial cells of the testes, which are critical for testosterone production. These toxins—often from processed foods, pesticides, and plastics—interfere with testosterone levels and damage the blood vessels responsible for penile blood flow, leading to weak erections and low libido. Research shows that by removing these toxins, you can restore healthy testosterone levels and improve blood flow, offering a real, long-lasting solution for ED.
Nitric Boost features a powerful, all-natural formula that includes:
Beetroot powder, which supports nitric oxide production and promotes healthy blood flow for firmer, longer-lasting erections.
Maca root, known for balancing hormones and boosting libido.
Catuaba, a natural aphrodisiac with stimulating properties.
Tribulus terrestris, traditionally used to increase testosterone and enhance sexual drive.
Epimedium, known for improving sexual performance and reducing fatigue.
This potent blend makes Nitric Boost a comprehensive solution for male sexual health—addressing both the root cause and the symptoms of erectile dysfunction.
With proven results and excellent quality of raw materials, NitricBoost is a smart choice for those who truly want to improve their sexual performance.
👉 Explore the Official Website to learn more about how Nitric Boost can help you take control of your sexual health and see why it’s gaining popularity in 2025.
#2 Prolong Power
7.4 / 10
TOTAL RANKING
B-
Overall Grade
Pros
- Contains 3 out of 5 must-have ingredients
- Vegan, non-GMO, and gluten-free
- Made in the USA
- Molecular formula similar to others on the market
Cons
- increased blood pressure
- Users report an unpleasant aftertaste when consuming prolong power
- ontains some ingredients with questionable efficacy and safety.
- A few users reported a slower onset of benefits.
After 40 days of use, the results of Prolong Power were mixed. Some users noticed slight improvements in endurance, but many reported little to no change in erectile function, along with some side effects like increased blood pressure.
Marketed as a natural solution for erectile dysfunction, Prolong Power combines Horny Goat Weed, Tongkat Ali, Saw Palmetto, Nettle Extract, Sarsaparilla, and Orchic Substance — ingredients known for their properties that help improve blood flow, increase testosterone production, and promote sexual health. However, recent research points to a deeper cause of erectile dysfunction: the accumulation of toxins in the testicular interstitial cells, which impairs testosterone production and damages the blood vessels of the penis. Unfortunately, this underlying issue is not addressed by the ingredients in Prolong Power.
User reviews on sites like Trustpilot reflect this inconsistency. While some customers noted minor energy improvements, others experienced no benefits or reported side effects such as dizziness and digestive discomfort.
At the moment, we do not recommend purchasing Prolong Power, as there are better and more effective alternatives.
#3 Alpha Boost
6.6 / 10
TOTAL RANKING
B-
Overall Grade
Pros
- Contains 2 out of 5 must-have ingredients
- Vegan, non-GMO, and gluten-free
- Made in the USA
- No fillers or artificial additives
Cons
- Focuses more on testosterone production rather than clinically proven mechanisms for enhancing overall male performance.
- Focuses more on testosterone production rather than clinically proven mechanisms for enhancing overall male performance.
- No clinical study
After 40 days of use, results from our analysis of Alpha Boost were inconsistent. Many participants reported little to no improvement in sexual performance, leading to mixed and often disappointing feedback.
Marketed as a testosterone and vitality enhancer, Alpha Boost is sold both on online marketplaces and the Verse Diagnostics website. However, the formula lacks transparency — there’s no clear breakdown of ingredients or their dosages, making it difficult to evaluate its true effectiveness. Scientific research on erectile dysfunction points to the role of toxin buildup in the testicular interstitial cells, which disrupts testosterone production and blood flow. Alpha Boost provides no clear solution for this root cause.
Customer reviews frequently mention a lack of noticeable results. The product is also missing essential credibility markers — such as clinical trials or a certificate of analysis. Additionally, being available on third-party marketplaces raises concerns about counterfeit versions, and the absence of a money-back guarantee further reduces consumer confidence.
With vague claims, minimal scientific support, and no clear path to addressing the core issues behind ED, Alpha Boost falls short of expectations — leaving many users disappointed and doubtful of its value.
#4 Vivalis Pro
5.0 / 10
TOTAL RANKING
C
Overall Grade
Pros
- Integrated with a product that millions of men already trust for boosting their testosterone levels.
- No artificial additives
- Vegan, non-GMO, and gluten-free
- Made in the USA
Cons
- No clinical study
- Does not contain alpha GPC.
- Users report an unpleasant aftertaste when consuming.
- Contains some ingredients with limited proof of efficacy
After 40 days of testing, Vivalis yielded underwhelming results for most participants. with many reporting no noticeable improvement in erectile function — resulting in largely negative feedback. Despite its claims of boosting endurance and sexual performance, the product failed to meet user expectations.
Sold exclusively through marketplaces like Amazon, Vivalis presents a vague ingredient profile, offering no clear disclosure of its active compounds or their dosages. This lack of transparency raises serious questions about its potential effectiveness. Scientific studies on erectile dysfunction increasingly highlight the role of toxin buildup in the testicular interstitial cells — a factor that impairs testosterone production and blood flow. Unfortunately, Vivalis does not appear to include ingredients designed to target this root cause.
User reviews on Amazon often cite little to no results, with some also reporting mild digestive side effects. The fact that the product is only available through third-party sellers heightens the risk of encountering counterfeit versions. Moreover, the absence of a money-back guarantee or verifiable clinical testing significantly weakens consumer trust.
With limited scientific support, unclear formulation, and no meaningful quality assurances, Vivalis struggles to deliver on its promises — leaving many users disappointed and doubtful of its effectiveness.
#5 Eroxon Gel
4.1/ 10
TOTAL RANKING
C-
Overall Grade
Pros
- No fillers or artificial additives
- Non-GMO and gluten-free
- Made in the USA
- Contains huperzine A
Cons
- Does not contain 4 out of 5 must-have ingredients
- Not vegan
- No clinical study
After 40 days of evaluation, Eroxon Gel delivered mixed and largely modest results.
Many patients reported an increase in blood pressure, resulting in lukewarm overall feedback.
Positioned as a fast-acting topical solution, Eroxon claims to enhance blood flow and trigger erections within 10 minutes. However, clinical data suggests it’s effective for only around 25% of men with mild erectile dysfunction — offering limited benefit for those with moderate to severe symptoms.
The formula consists primarily of alcohol, glycerin, and propylene glycol, designed to produce a cooling effect. However, it lacks key botanical extracts or nutrients commonly associated with long-term support for erectile health. Moreover, it does not address the core issue highlighted in ED research: toxin accumulation in the testicular interstitial cells, which impairs testosterone production and blood circulation.
Customer feedback on platforms like Amazon reflects this limitation, with an average rating of 2.1 out of 5. Common complaints include lack of results, skin irritation, and the gel’s impracticality for spontaneous moments due to its messy application.
Without long-term clinical validation or ingredients that target the underlying causes of ED, Eroxon Gel offers only temporary relief — and even that, for a narrow group of users.
NITRICBOOST - A Better Alternative?
NITRIC BOOST
NITRICBOOST is a powerful male performance and energy supplement that has shown impressive results in supporting sexual health. Its all-natural, science-backed formula is designed to help men improve erectile function, boost stamina, and restore confidence safely and effectively. In surveys, over 85% of users reported a noticeable increase in energy levels and sexual vitality when taken as directed. Its potent blend of clinically supported ingredients works to reduce toxin buildup, support testosterone production, and promote healthy blood flow—key factors in achieving and maintaining firm erections. Within the first 40 days, more than 88% of users noted improvements in libido, endurance, and overall sexual performance. Discover more about NitricBoost right now.
It’s important to note that we don’t receive any compensation for these tips. They are based on studies of some of the top products being marketed in 2025, which we decided to analyze thoroughly in order to help as many men as possible restore and improve their sexual health.
3 Tips for Successfully Managing Erectile Dysfunction:
Be mindful during meals: Avoid distractions, like your phone, as it can help prevent overeating, which negatively impacts cardiovascular health and contributes to erectile dysfunction.
Start a food diary: Monitoring your intake helps identify eating patterns that may affect blood circulation and, consequently, erectile function. Simple dietary changes can make a big difference.
Always read nutritional labels: When shopping, choose foods that promote heart health and circulation, such as those rich in antioxidants and nutrients that support healthy blood flow.
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